Now it is proved that cholera may be caused by Vibrio cholerae biotype following: a) classical Vibr

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Cholera - particularly infectious disease caused by Vibrio cholerae and their toxins that penetrate through the mouth in the digestive crrt renal tract of healthy susceptible humans. The disease is accompanied by increased permeability of cell membranes of the epithelium of the mucous membrane of the small intestine for water and mineral salts takes place at profuse discharge them from the body with a liquid feces, as well as vomit, characterized by dehydration, disorders of fluid and electrolyte balance, hemodynamics and renal function.
Now it is proved that cholera may be caused by Vibrio cholerae biotype following: a) classical Vibrio cholerae (V.comma), opened in 1833 by R. Koch b) cholerae El Tor (V. cholerae EL-Tor). By its construction cholerae both types does the same but have different ability lyzyruvatysya bacteriophages. Cholerae biotype data are gram-negative bacilli, are slightly curved or cylindrical komopodibni crrt renal bacteria having at one of its ends flagellum and therefore carry very active crrt renal translational motions. crrt renal Body microbe contains somatic O-antigen and flagellum - H-antigen. Vibrio cholerae grow well on artificial nutrient media with an alkaline reaction. Vibrio cholerae classical and El Tor sirolohichnyh divided into two types: Ogawa and Inaba. Cholera toxin forming three types, among which the most important in the pathogenesis choleragen. Actual agglutinated Vibrio cholerae O-serum. Alkaline reaction medium, which are Vibrio cholerae, promotes their survival and reproduction. In the acidic environment of vibrio die quickly.

Disinfectants are harmful crrt renal to them. Under certain conditions in the environment for a long time, they retain their viability, for example if they are in the water. However, cholera is easily killed when exposed to high temperatures or direct sunlight. The role of the main sources of infection with cholera Play patients who are in acute manifestations of this infection, especially people who suffer alhidnoyu form and rekonvalistsenty in the first 4-5 days after attenuation main symptoms. Patients alhidnoyu form of cholera isolated from liquid feces and vomit (in both cases - such as rice broth) a huge number of vibrios. Patients erased, atypical clinical forms, as well as those who were in contact with patients and are temporary

(transient) carriers, Vibrio cholerae released in much smaller quantities crrt renal than alhidniy form of cholera, although these individuals have some epidemiological crrt renal significance. Vibriononosinnya can continue to 1-1.5 months. and even much more. We must carefully identify crrt renal all cases of cholera, in time to isolate patients, spending crrt renal a full range of preventive measures, and in infectious hospitals where they were taken, to make reliable disinfection of their selections

before crrt renal going into the general sewer. When the cholera cases in this village created emergency anti-epidemic commission and staff epidemic focus, endowed with adequate powers and coordinating all work to combat the spread of infection. Identified patients crrt renal with clinically severe forms of cholera crrt renal placed crrt renal in infectious (Vibrio) hospital, which should serve well-trained medical personnel. Recovering after undergoing a cholera should crrt renal be placed separately from patients who are in acute disease. To identify patients with cholera among persons with clinical symptoms that cause varying degrees of suspicion for the possibility of their cholera, are "Extraembryonic" special insulators or hospital, it makes it possible not only to detect cholera patients, but also to begin their possible crrt renal earlier treatment of locally or to the transfer to the infectious hospital. System "provisionally" hospitals can not only lead clinical observation of persons who were in the focus of infection, but also to conduct their thorough bacteriological examination, thus revealing even the deleted forms of the disease and vibriononosinnya. Mode to "provisionally" hospitals is the same as in cholera. In centers where identified crrt renal cases of cholera, it is necessary to conduct monitoring of practically healthy persons more or less exposed to risk of infection. These persons placed 6 days observatory for clinical and bacteriological observation that corresponds to the maximum length of the incubation period of cholera. Thereafter, in the absence of K