Lincomycin hydrochloride belongs to a group linkozamidnyh sonaki shower head bacteriostatic agents. This means that the drug acts primarily on the interruption of the process of reproduction of pathogenic sonaki shower head microorganisms. Pharmacological activity is detected only in respect of Gram-positive pathogens. sonaki shower head All Gram-negative pathogens, protozoa, viruses and fungi possess a high degree of resistance to lincomycin.
At the same time, lincomycin instructions for use can be used not only as bacteriostatic agents. In large doses exceeding therapeutic, this drug can cause massive irreversible destruction of microorganisms. This property allows to develop flexible lincomycin treatment regimens of various inflammatory diseases. So, the first day can be used drums dose to kill adult organisms. Further possible therapeutic dose maintenance treatment to prevent re-contamination and early growth of bacteria in the body.
Pharmacological industry produces a variety of dosage forms lincomycin. This makes it easy to use and creates difficulties for use even at home. The most popular are the injections and pills lincomycin. also apply ointment and eye drops. Lincomycin Hydrochloride and its pharmacological action
Lincomycin hydrochloride in sufficient quantity is absorbed from the digestive tract. But there are some conditions for its proper administration. In particular, lincomycin be taken orally or 30 minutes before a meal or 1-1,5 hour thereafter. May reduce the effectiveness of the process of absorption from the stomach by 50%. With the proper administration of the gastrointestinal absorbed a total of 40% of the active ingredient. In human blood drug determined 30 minutes after administration. Therapeutic concentration is maintained at a high level for several hours.
In intramuscular sonaki shower head in plasma gets 100% of the active substance and its half-life is more than 6 hours. This allows you to do 1-2 injections per day to maintain therapeutic concentrations. Lincomycin hydrochloride easily penetrates through sonaki shower head all the barriers found in the cerebrospinal fluid, blood, brain, cerebrospinal fluid, bile, urine. This feature allows the use of a drug for severe generalized infections such as sepsis, peritonitis, inflammation of the membranes of the brain, heart disease, liver and kidney.
After penetration into the body lincomycin antibiotic binds to blood proteins and transported to places where bacterial colonies. sonaki shower head In the inflammation violates protein synthesis of cell membranes and prevents splitting and multiplication of bacteria. In large doses destroys the bacteria cell membrane and makes it non viable. Lincomycin sonaki shower head drug: use in dentistry and treatment of diseases
Lincomycin in dentistry is used for treating and preventing inflammatory diseases. This drug raids high activity against microorganisms that cause tooth decay tooth enamel. Therefore, in some cases, dentists prescribe mouthwashes and blending solutions lincomycin ointment to the affected gums. After tooth extraction lincomycin in dentistry used to prevent sonaki shower head secondary infection accession to the wound surface in the hole.
In the treatment of diseases of lincomycin therapy is widely used in: lobar pneumonia, cystitis sonaki shower head and acute pyelonephritis, sepsis blood and peritonitis, acute appendicitis, septic endokarditah, sonaki shower head spider inflammation of the meninges, extensive hematomas in the brain, cholecystitis, infectious colitis.
Most lincomycin application is in specialized sonaki shower head hospitals. This is due to many contraindications and side effects that made this antibiotic. Especially dangerous are the disruption of hematopoiesis in the use of lincomycin in large doses. This may manifest as leukopenia and decrease the number of platelets, which leads to proffuznym bleeding and reducing immunity of the patient. After discontinuation of therapy, these figures pattern of peripheral blood slowly coming back to normal.
It should also be noted side effects from the digestive system. It can be observed liver dysfunction, manifested in the form of increased transaminases, the appearance of skin itching, jaundice chemical origin. Severe cases may develop hepatic coma.
For external use ointment used lincomycin. The main indications for its use - it rozhistye inflammation, suppurating wound surfaces, adherence to infection sonaki shower head of burns. Lincomycin dosage depending on how you use Lincomycin tablets 1 tablet 4 times a day. Intramuscular injections of lincomycin 2 ml 2 times a day. Intravenous injections of 2 ml lincomycin (600 mg) +10 ml 0.9% sodium chloride solution 1 time per day. Lincomycin thin layer of ointment or sterile Servet
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.