When administered easily average water used in shower absorbed, Cmax in plasma observed after 1-2 h

Stabilizes cell membranes, including lysosomal average water used in shower

reduces average water used in shower the yield of proteolytic enzymes from lysosomes (braking phase alteration and limitation average water used in shower inflammation), inhibits phospholipase A2, gives lyberatsyya arachidonic acid and, consequently, inhibits the synthesis of PG, hydroxy acids and leukotrienes, inhibits the activity of hyaluronidase and reduces capillary permeability (suppression phase exudation ), fibroblast activity (inhibition of proliferation phase). Antiallergic properties due to violation of degranulation of mast cells, a decrease in the synthesis of leukotrienes and suppression of antibody production, protyshokovi - delay of sodium and water, increasing the reaction

vessels to endogenous and exogenous vasoconstrictor substances and stimulating average water used in shower effect on cardiac function, antitoxic - accelerated inactivation of toxic substances in the liver, decreased average water used in shower permeability of cell membranes.
When administered easily average water used in shower absorbed, Cmax in plasma observed after 1-2 h bioavailability over 90%. Boitransformed, mainly in the liver, excreted mainly by the kidneys. With increasing doses increased T1 / 2, total clearance, volume of distribution and the degree of protein

binding. Influences on carbohydrate, protein, fat and water-salt metabolism. Increases blood glucose levels, promotes the accumulation of glycogen average water used in shower in the liver, increasing gluconeogenesis. Enables processes catabolism slows regeneration, average water used in shower controls deamination of amino acids in the liver, promotes redistribution of fat tissue in the body retains sodium and water, average water used in shower increases the excretion of potassium and stimulates the cardiovascular system, increases arteriolar tone and myocardial contractility,

increases stroke and minute volume , stimulates the central nervous system, has anti-toxic and immunosuppressive average water used in shower effects, causes increased secretion of gastric mucosa and gastric acidity. Indications.
Rheumatism, rheumatoid arthritis, dermatomyositis, periarteritis nodosa, scleroderma, ankylosing spondylitis, asthma, allergic disease, Addison's disease, acute adrenal insufficiency, adrenogenital syndrome, hepatitis, hepatic coma, hypoglycemic states, lipoid nephrosis, agranulocytosis, various forms of leukemia, Hodgkin, thrombocytopenic purpura, hemolytic anemia, average water used in shower infectious mononucleosis, acute pancreatitis, pemphigus, eczema, pruritus, exfoliative dermatitis, psoriasis, prurigo, seborrheic dermatitis, lupus erythematosus, erythroderma, alopecia, prevention and treatment of shock. Contraindications.
Hypersensitivity, peptic ulcer and duodenal ulcer in acute phase, osteoporosis, pituitary - Cushing, susceptibility to thromboembolism, renal failure, severe hypertension, average water used in shower systemic fungal infections, viral infections average water used in shower during vaccination, active TB, productive symptoms in mental disorders. Restrictions apply.
Reduced resistance to infection, hyperglycemia until the development of steroid diabetes, negative nitrogen balance, osteoporosis, aseptic bone necrosis, increased gastric acidity, ulcerogenic effect on the digestive tract, hypokalemia, retention of sodium and water, edema, hypertension, increased blood clotting syndrome, pituitary - Cushing, weight gain, "moonlike" face, steroid average water used in shower cataract, glaucoma average water used in shower latent, menstrual irregularities in women, insomnia, muscle weakness withdrawal syndrome associated average water used in shower with the inhibition of function or atrophy of the adrenal cortex. average water used in shower Interaction.
Accelerates the elimination of barbiturates, dyhitoksyn, penicillin, chloramphenicol. Phenobarbital, diphenine,

diphenhydramine, ephedrine increase the rate of biotransformation. The risk of hypokalemia increases in combination with amphotericin average water used in shower B and cardiac average water used in shower glycosides. NSAIDs increase (mutually) average water used in shower ultserohennist. When combined with aspirin may develop gipoprotrombinemii. Dosage.
Inside. For adults the initial dose - 20-30 mg, maintenance dose - 5-10 mg. If necessary, the initial dose may be 15-100 mg per day maintenance - 5-15 mg. The daily dose should be reduced gradually. For children

the starting dose is 1-2 mg / kg body weight per day in 4-6 receptions, the maintenance - 300-600 mg / kg per day. The highest single dose for adults - 15 mg daily - 100 mg. In urgent situations using large doses for a short time. Source: zdorovieinfo.ru Pohozhye article average water used in shower
Prednikarbat * The active average water used in shower substance (INN) Russian average water used in shower title: Prednikarbat * Latin name: Prednicarbate * Chemical name. Farmakolohiya.Mistsevyy anti-inflammatory effect is due to stimulation of synthesis lipokortynu, inhibiting phospholipase ...
Enap. Instructions for use and contraindications drug enap has a pronounced antihypertensive effect which is due to blockade of ACE anaprilatom. Thus, under the action of the drug in the blood decreases ...
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